Metabolic syndrome and schizophrenia

by Dr Arijit Bose and Dr Sepehr Hafizi


Last updated: October 2019


The World Health Organization (WHO) has recognised metabolic syndrome as a global epidemic (Potenza & Mechanick, 2009). Its causes are not fully understood but its consequences can be severe, including type 2 diabetes mellitus and cardiovascular disease.


Contributory factors include an unhealthy diet, smoking, genetics, lack of exercise and excess alcohol. It is a common comorbidity in people with schizophrenia and, in addition, some antipsychotics may worsen the risks.

Appropriate intervention by clinicians can reduce the risk of mortality and morbidity. This module will offer a framework to help with the diagnosis of metabolic syndrome and will advise on appropriate treatment paths for patients at risk.

This module will answer the following questions:

  • What is metabolic syndrome and how is it diagnosed?


  • What is the link between schizophrenia and metabolic syndrome?


  • What is the relationship between antipsychotics and metabolic syndrome?


  • Why is it difficult to manage patients with both schizophrenia and metabolic syndrome?


Start the module


If you like this module, you may also be interested in:


Alcohol-related brain damage by Professor Kenneth Wilson et al


First-episode psychosis: Part 1 and Part 2 by Dr Andrew Thompson et al


Social functioning in schizophrenia by Dr K. Thyarappa Praveen and Dr Rob Macpherson




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